The aim of this project is to utilize 3D printing and bioprinting techniques to reconstruct bone defects by combining stem cells from adipose tissue and bone marrow, and biocompatible biomaterials to support personalized bone regeneration.
A library of bioinks (hydrogels and stem cells) will be prepared, printed, and tested in different animal models. The overreaching goal is to facilitate clinical translation on 3D printing techniques for bone regeneration.
The project is a partnership between three institutions in two Nordic countries – University of Bergen (UiB) and Haukeland University Hospital (HUH), Norway and Tampere University (TUNI), Finland.
Yamada, S., Ockermann, P. N., Schwarz, T., Mustafa, K., & Hansmann, J. (2023). Translation of biophysical environment in bone into dynamic cell culture under flow for bone tissue engineering. Computational and Structural Biotechnology Journal.
Ali, H. R., Suliman, S., Osman, T. A. H., Carrasco, M., Bruland, O., Costea, D. E., … & Mustafa, K. (2023). Xeno-free generation of human induced pluripotent stem cells from donor-matched fibroblasts isolated from dermal and oral tissues.
Shanbhag, S., Kampleitner, C., Al-Sharabi, N., Mohamed-Ahmed, S., Apaza Alccayhuaman, K. A., Heimel, P., … & Gruber, R. (2023). Functionalizing Collagen Membranes with MSC-Conditioned Media Promotes Guided Bone Regeneration in Rat Calvarial Defects.
Hassan, M. N., Yassin, M. A., Eltawila, A. M., Aladawi, A. E., Mohamed-Ahmed, S., Suliman, S., … & Mustafa, K. (2022). Contact osteogenesis by biodegradable 3D-printed poly (lactide-co-trimethylene carbonate).